Size

1000ug

Catalog no#

GEN660245

Price

542 EUR

Tested applications:

N/A

Gene name synonims

N/A

Concentration

N/A

Other gene names

N/A

Clone

3D6

Host organism

N/A

Gene name

RT-1B

Category

Antibodies

Clonality

Monoclonal

Also known as

MHC Class II

Subcategory

Mnoclonal antibodies

Immunoglobulin isotype

IgG1, kappa for MAb 3D6

Latin name

Mus musculus,Rattus norvegicus

Purification method

Chromatography on protein A Sepharose

Form/Appearance

PBS, pH 7.4, 0.1 % sodium azide (NaN3)

Storage and shipping

Store the antibody at +4 degrees Celsius.

Other names

MHC class II beta chain, partial; MHC class II beta chain; N/A; N/A; MHC class II beta chain

Species reactivity

N/A; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antigens are peptides or recombinant or native dependent on the production method.

Specificity and cross-reactivity

MHC class II RT-1B antigen. MAb reacts with monomorphic determinant on beta chain of RT-1B molecules. MAb 3D6 does not cross-react with RT-1A,-C,-D rat MHC products.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Test

Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.

About

Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.