Size

1 mililiter

Catalog no#

GEN631981

Price

658 EUR

Concentration

N/A

Immunoglobulin isotype

IgG2b

Clone

3F272

Category

Antibodies

Clonality

Monoclonal

Also known as

Melanoma, gp100

Subcategory

Mnoclonal antibodies

Source organism

Human (Homo sapiens)

Host organism

Mouse (Mus musculus)

Tested applications:

Immunohistochemistry (IHC)

Purification method

Affinity Purified by Protein G affinity chromatography.

Other gene names

PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S

Gene name synonims

PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S

Gene name

PMEL; PMEL; P1; SI; SIL; ME20; P100; SILV; ME20M; gp100; ME20-M; PMEL17; D12S53E; D12S53E; PMEL17; SILV; ME20M; ME20-S; ME20S

Form/Appearance

Supplied as a liquid in PBS, pH 7.4. No stabilizing proteins added. No preservative added. Also available with BSA and sodium azide. See M2869-01.

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Description

Antigens are peptides or recombinant or native dependent on the production method.Sodium azide NaN3 is often used to prevent antibody degradation in 0,02% W/V concentrations. MBS Monoclonals supplies azide free antibodies on request.Recently MBS Monoclonals made this Melanoma, gp100 (Melanoma Associated Antigen) (BSA ) available without azide. It will stick less and is more suitable for ELISA or in vivo studies. However you need to store the @VV@ frozen and ship on dry ice.

Specificity and cross-reactivity

Recognizes a human (pre)melanosomal 100+7kD antigen (glycoprotein). Reacts with melanomas, clear cells sarcomas (melanoma of soft tissue), nevocellular nevi and normal melanocytes. Except for one case of non-Hodgkin's lymphoma in which macrophages were positive, no reactions with other tumors or tissues have been observed.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Other names

melanocyte protein PMEL isoform 3 preproprotein; Melanocyte protein PMEL; melanocyte protein PMEL; melanocyte protein mel 17; silver, mouse, homolog of; melanocyte protein Pmel 17; melanosomal matrix protein17; silver locus protein homolog; melanoma-associated ME20 antigen; melanocytes lineage-specific antigen GP100; premelanosome protein; ME20-M; ME20M; Melanocyte protein Pmel 17; Melanocytes lineage-specific antigen GP100; Melanoma-associated ME20 antigen; P1; P100; Premelanosome protein; Silver locus protein homologCleaved into the following 2 chains:M-alpha; Alternative name(s):; 95 kDa melanocyte-specific secreted glycoprotein; P26; Secreted melanoma-associated ME20 antigen