Size
1 mililiter
Catalog no#
GEN633137
Price
586 EUR
Concentration
N/A
Gene name
N/A
Gene name synonims
N/A
Other gene names
N/A
Other names
N/A
Clone
3G75
Immunoglobulin isotype
IgM,k
Purification method
Purified
Category
Antibodies
Clonality
Monoclonal
Also known as
CD15, Granulocytes
Subcategory
Mnoclonal antibodies
Host organism
Mouse (Mus musculus)
Source organism
Human (Homo sapiens)
Tested applications:
Immunohistochemistry (IHC)
Form/Appearance
Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.1% sodium azide.
Description
Antigens are peptides or recombinant or native dependent on the production method.
Species reactivity
Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Storage and shipping
Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Specificity and cross-reactivity
CD15 stains a variety of tumor cells, including breast and lung cancer cells. In a series of 98 breast tumors, CD15 stained 35% of breast carcinomas, 60% of hyperplasias and 45% of normal breast tissues. (8) In the breast, CD15 expression is closely associated with the leading edge of invasive tumors. In non-small cell lung cancers, CD15 stained 56% of adenocarcinoma and 45% of squamous cell carcinoma in one study. (9) As CD15 stained adenocarcinoma but not mesothelioma, it has been used as part of an antibody panel to distinguish adenocarcinoma from malignant mesothelioma.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.