Size

10 μg

Catalog no#

abx165524

Price

338 EUR

Raised in

N/A

Clonality

N/A

Target

1 Protein

Purification

Affinity purified

Category

Proteins And Peptides

Stock availability

Shipped within 5-12 working days.

Immunogen

see included datasheet or contact us

Footnote

This product is for research use only.

Applications

WB (for other applications please contact us)

Species reactivity

Human, Mouse, Rat (for other species please inquire)

Storage conditions

Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Description

Antigens are peptides or recombinant or native dependent on the production method.

Gene

Ovalbumin (abbreviated OVA) is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin displays sequence and three-dimensional homology to the serpin superfamily, but unlike most serpins it is not a serine protease inhibitor. The function of ovalbumin is unknown, although it is presumed to be a storage protein. OVA is also the best characterized and the first antigen proteins used as a transgene to make transgenic mice. Many different transgenic mouse models have systemic OVA expression driven by the ubiquitously expressed b-actin promoter or tissue-specific OVA expression with insulin promoter to drive the transgene expression, for studying type I diabetes, or in different isoforms, secreted or cell-membrane associated, and more recently as inducible transgene models. These C57BL/6 mice, BALB/c mice models are well characterized, and have contributed to our understanding of immunogenicity and tolerance by the OVA model.