Size
10µg
Catalog no#
PKSH032949-10µg
Price
267 EUR
Activity
NA
Fusion tag
C-6His
AP Mol Mass
35 kDa
Accession
P07288
Tissue
prostate
Mol Mass
27.1 kDa
Expressed Host
Human cells
Group
recombinants
Sequence
Ile25-Pro261
Source
Recombinants or rec. proteins
Purity
＞95% as determined by reducing SDS-PAGE.
Endotoxin
＜1.0 EU per µg as determined by LAL test.
Description
Antigens are peptides or recombinant or native dependent on the production method.
Formulation
Supplied as a 0.2 μm filtered solution of 20mM TrisHcl, 150mM NaCl,1mM CaCl2,pH7.5.
Stability and Storage
Store at < -20℃, stable for 6 monthshs after receipt.Please minimize freeze-thaw cycles
Synonym
Prostate-specific antigen;PSA;Gamma-seminoprotein;Kallikrein-3;P-30 antigen;Semenogelase;KLK3;APS
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Background
KLK3, also known as APS, is short for Prostate-specific antigen. It is a 261 aa. protein which belongs to the peptidase S1 family and Kallikrein subfamily. This protein has 5 isforms produced by alternative splicing. It is a secreted protein and can forms a heterodimer with SERPINA5 which can inhibit its activity. KLK3 is also strongly inhibited by Zn2+, 100 times more abundant in semen than in serum. This inhibition is relieved by exposure to semenogelins, which are avid zinc binders. KLK3 can hydrolyzes semenogelin-1 thus leading to the liquefaction of the seminal coagulum.