Size
10µg
Catalog no#
PKSH032112-10µg
Price
267 EUR
Activity
NA
Tissue
cell
Fusion tag
N-Trx
Accession
P21854
Expressed Host
E.coli
Mol Mass
30.6 kDa
Group
recombinants
AP Mol Mass
14&17&32 kDa
Sequence
Arg117-Cys226
Source
Recombinants or rec. proteins
Purity
＞90% as determined by reducing SDS-PAGE.
Endotoxin
＜1.0 EU per µg as determined by LAL test.
Synonym
B-Cell Differentiation Antigen CD72; Lyb-2; CD72
Formulation
Lyophilized from a 0.2 μm filtered solution of 20mM PB,150mM NaCl,pH7.4.
Shipping
The product is shipped at ambient temperature.Upon receipt, store it immediately at the temperature listed below.
Description
Antigens are peptides or recombinant or native dependent on the production method.For cells, cell lines and tissues in culture till half confluency.
Stability and Storage
Lyophilized protein should be stored at < -20℃, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7℃ for 2-7 days.Aliquots of reconstituted samples are stable at < -20℃ for 3 months
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
Background
B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.