Size

200ug

Catalog no#

GEN631840

Price

669 EUR

Concentration

N/A

Immunoglobulin isotype

IgG1

Clone

10B1430

French translation

anticorps

Category

Antibodies

Clonality

Monoclonal

Tissue

cell, lymphocyte

Host organism

Mouse (Mus musculus)

Subcategory

Mnoclonal antibodies

Source organism

Human (Homo sapiens)

Also known as

NKp46, Natural Cytotoxicity Receptor

Tested applications:

Western Blot (WB), Flow Cytometry (FC/FACS)

Purification method

Affinity Purified by Protein G affinity chromatography.

Form/Appearance

Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide.

Other gene names

NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46

Gene name synonims

NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46

Gene name

NCR1; NCR1; LY94; CD335; NKP46; NK-p46; LY94; NK-p46; NKp46; hNKp46

Properties

If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.

Species reactivity

Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.

Other names

natural cytotoxicity triggering receptor 1 isoform a; Natural cytotoxicity triggering receptor 1; natural cytotoxicity triggering receptor 1; NK cell-activating receptor; natural killer cell p46-related protein; lymphocyte antigen 94 homolog (activating NK-receptor; NK-p46); natural cytotoxicity triggering receptor 1; Lymphocyte antigen 94 homolog; NK cell-activating receptor; Natural killer cell p46-related protein

Specificity and cross-reactivity

Recognizes the human natural cytotoxicity receptor CD335, also known as NKp46. NKp46 is expressed on circulating NK cells and is reported to be a novel NK-specific cell surface molecule that is involved in human NK cell activation.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.

Storage and shipping

Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months the antibody should be stored at -20 degrees Celsius.. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Description

Antigens are peptides or recombinant or native dependent on the production method.For cells, cell lines and tissues in culture till half confluency.The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.